5 December 2022

Mechanism and Comorbidities of Headache and Facial Pain

Develop examination and treatment strategies through insight into disease mechanisms and comorbidity.


This course will focus on complex pathophysiological mechanisms underlying headache and facial pain disorders, and the role of comorbidities in neurobiology of headache disorders.

We will cover the most important theories/hypotheses, discovery in genetics, strengths and limitations of animal and human studies, animal models of secondary headaches.















During the course, the participants will gain detailed insights into the existing knowledge about underlying genetic and pathophysiological mechanisms of primary and secondary headache disorders as well as facial pain.

Participants will acquire knowledge about the mechanisms underlying the most common comorbid conditions for headache disorders and their relevance to disease development and treatment. Moreover, participants will acquire knowledge about existing in vitro and in vivo experimental headache models.

Communication based on a well-balanced scientific background
Participants will learn to understand, discuss and critically assess the scientific literature in the area of genetics and disease mechanisms. They will learn to communicate this to patients and their families, as well as to their own colleagues, based on a well-balanced scientific background.

Furthermore, participants will be able to develop a basis for understanding the examination and treatment strategies through insight into disease mechanisms and comorbidity.

On completion of the course, the participants should have acquired the prerequisites for participating in or initiating new scientific investigations of disease mechanisms and treatment. Lastly, participants will be able to optimize the treatment process and contribute to a critical assessment of new treatment strategies on a scientific basis.














Course details

Duration: 5 weeks; 5 days on campus
5 December 2022 - 6 January 2023 (e-learning) and
9-13 January 2023 (campus)
Only available every second year
Place: University of Copenhagen, Copenhagen, Denmark
Course fee:
EU/EEA citizens: 10,000 DKK
Non-EU/EEA citizens: 15,100 DKK
Level and credit: Master's course; 7.5 ECTS
Examination: Exam date 
Application deadline:
Course: 10 October 2022
Master of Headache Disorders: 1 May 2022
Admission: To be admitted, you must meet the admission criteria for Master of Headache Disorders 

The opening of the application period is announced via the programme newsletter.
Download course curriculum