Alexandra Sinclair graduated from the University of Birmingham School of Medicine in 2000 and attained her MRCP in 2003. She attained her PhD in 2010 and subsequently worked as an NIHR Clinical Lecturer in Neurology. She now works as Neurology Consultant & Clinician Scientist with a role combining clinical neurology with translational research focusing on idiopathic intracranial hypertension (IIH) the University of Birmingham. Alongside IIH clinical trials her lab uses in vitro and in vivo models to assess the relationship between neuroendocrine pathways and intracranial pressure regulation. She runs the headache service and the multidisciplinary IIH service at University Hospital NHS Foundation Trust.